Campaign. This is the bulk of Left 4 Dead 2's content. There are 5 separate levels, each of which will take up to 2 hours, depending on how often you die, the number of players taking part and the difficulty level. You can play in split-screen on Xbox 360 (if additional controllers are connected), or online with up to four-players.
For US players there are also US West and US East Official servers so again it depends on the game mode. Campaign and Versus are the most popular modes and there are always players for them. And by the way, L4D2 is still the top 100 most played game on Steam.
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left 4 dead 2 how many players